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  • Stem Cells in Orthopedic Rheumatology: Where Clinical Signals Are Strongest

    Stem-cell therapies in orthopedic rheumatology offer dual promise: immunomodulation and tissue repair. This editorial reviews 2023-2025 evidence across key rheumatic diseases, identifying where clinical signals are strongest. Mesenchymal stromal/stem cells (MSCs) show encouraging immunologic and symptomatic benefits in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), particularly lupus nephritis, with acceptable short-term safety. However, trial heterogeneity in MSC source, dose, and manufacturing limits reproducibility.

    Source: ResearchGate

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  • Pediatric Elbow Dislocation With Comminuted Fractures of the Medial Humeral Epicondyle and Trochlea

    Elbow dislocations in children are uncommon and often occur alongside fractures, most frequently of the medial epicondyle. Concurrent dislocation with fractures of both the medial epicondyle and the trochlea is exceptionally rare. We present an unusual case of an 11-year-old boy with elbow dislocation associated with comminuted fractures of the medial humeral epicondyle and trochlea.

    Source: Cureus

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  • Exercise interventions for rotator cuff-related shoulder pain in middle-aged and older adults: a systematic review and meta-analysis

    Rotator cuff-related shoulder pain is highly prevalent in middle-aged and older adults and is associated with pain, functional limitations, and reduced quality of life. This systematic review and meta-analysis aimed to evaluate the effectiveness of exercise-based interventions on pain, function, range of motion (ROM), and strength in middle-aged and older adults with rotator cuff-related shoulder pain.

    Source: Springer Nature

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  • What Is a Torn Triceps Injury?

    A torn triceps injury involves damage to the muscle or tendon at the back of your upper arm, often requiring medical attention. Recovery can be lengthy, with treatment options ranging from conservative methods to surgery, depending on the severity

    Source: Verywell Health

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  • Treatment to Heal From Golfer s Elbow

    Golfer’s elbow, or medial epicondylitis, is a condition caused by overuse of the elbow’s tendon flexor, leading to pain on the inside of the elbow. Often, you can effectively treat and manage this condition at home, but you may need to see a provider to regain comfort and mobility.

    Source: Verywell Health

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  • Shoulder Subluxation: Healing a Partially Dislocated Shoulder Injury

    Shoulder subluxation, a partial dislocation, occurs when the humerus bone partially slips out of the shoulder socket. Understanding the causes and treatments, such as braces and exercises, can help manage pain and prevent further injury.

    Source: Verywell health

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  • Boost Shoulder Strength With Isometric Exercises

    Isometric shoulder exercises offer a gentle method to strengthen your rotator cuff and boost mobility, making them ideal for rehabilitation. Start your recovery journey with these safe techniques.

    Source: Verywell health

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  • What Causes Neck and Shoulder Pain?

    Pain in the neck and shoulders is frequently linked because these areas share muscles and nerves. Identifying the cause is key to managing your discomfort.

    Source: Verywell health

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  • Biological Treatment in Meniscus Injury

    Meniscal injuries, common in sports, often cause knee pain and instability. The meniscus plays a key role in pressure distribution and joint stability, making its repair essential. Treatments range from conservative approaches to surgical interventions, with growing interest in biological factors such as growth factors, mesenchymal stem cells, platelet-rich plasma, fibrin clot, and tenocyte to enhance healing. This review compares the effects of these biological agents in meniscal repair, examining their mechanisms, limitations, and clinical outcomes.

    Source: Formosan Journal of Musculoskeletal Disorders

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  • Biologics for bone regeneration: advances in cell, protein, gene, and mRNA therapies

    Bone fractures represent a significant global healthcare burden. Although fractures typically heal on their own, some fail to regenerate properly, leading to nonunion, a condition that causes prolonged disability, morbidity, and mortality. The challenge of treating nonunion fractures is further complicated in patients with underlying bone disorders where systemic and local factors impair bone healing. Traditional treatment approaches, including autografts, allografts, xenografts, and synthetic biomaterials, face limitations such as donor site pain, immune rejection, and insufficient mechanical strength, underscoring the need for alternative strategies.

    Source: Nature

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